Manufacturer: Sun Pharma
Pharmaceutical name: Olmesartan Medomoxil
Pack: 10 pills (10 mg)
Olmezest is a medication that functions as an angiotensin II receptor blocker, utilized for managing hypertension in individuals with elevated blood pressure who are predisposed to cardiovascular issues, aiming to avert strokes and heart attacks. It effectively brings blood pressure down to normal resting levels, facilitating better heart function and decreasing the chances of cardiovascular diseases and damage to vital organs. Olmezest can be administered alone or alongside other antihypertensive drugs, such as diuretics (commonly known as water tablets).
Olmezest contains Olmesartan Medoxomil, which is an angiotensin II receptor blocker (ARB). This compound works by inhibiting the interaction of the hormone angiotensin II with its receptor found in various tissues, including the walls of blood vessels (vascular smooth muscle) and kidney cells. Angiotensin II is a hormone produced by the body that plays several roles in blood pressure regulation, which is the pressure required to circulate blood throughout the body, as well as maintaining fluid balance—the quantity of water the kidneys filter from the blood. Angiotensin II triggers the retention of salt (sodium and potassium) and water by the kidneys, while also causing the contraction of blood vessels. This leads to an increased blood volume and a simultaneous decrease in the volume of blood vessels, consequently elevating blood pressure. In Olmezest, Olmesartan obstructs the attachment of Angiotensin II to its receptor, thereby hindering its blood pressure-raising effects, resulting in the widening of blood vessels and enhanced elimination of salt and water through urine by the kidneys, collectively leading to a reduction in blood pressure.
The most frequently reported adverse effects associated with Olmezest include: upper respiratory tract infections such as sinusitis or bronchitis, flu-like symptoms, dizziness, cough, diarrhea, nausea, abdominal discomfort, headaches, fatigue, back pain, peripheral edema, and alterations in blood salt levels.